Flow measurement by using the signal decrease of moving scatterers in spatially encoded fourier domain optical coherence tomography

Research output: Contribution to journalConference articleContributedpeer-review

Abstract

Blood flow measurement with spectrometer-based Fourier domain optical coherence tomography (FD-OCT) is limited by the motion-induced signal fading and the resulting reduction of flow sensitivity. Therefore, we have numerically simulated the signal power decrease of an obliquely moved scattering layer as a function of the absolute sample velocity composed of an axial and transverse component. In contrast to the prevalent expectance, the resulting signal damping is not only the sum of axial and transverse effect. In this study, we take advantage of the signal decay and present the feasibility to quantify high flow velocities at which the standard Doppler OCT does not work any longer. For the validation of our approach, a flow phantom model consisting of a 1%-Intralipid solution and a 320 μm glass capillary was used. With this phantom study, depth-resolved flow was visualized and the quantitative velocities were extracted from the OCT images without phase information.

Details

Original languageEnglish
Article number71681S
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7168
Publication statusPublished - 2009
Peer-reviewedYes

Conference

TitleOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII
Duration26 - 28 January 2009
CitySan Jose, CA
CountryUnited States of America

External IDs

Scopus 65349159206
ORCID /0000-0003-0554-2178/work/142249839
ORCID /0000-0003-2292-5533/work/142256578

Keywords

Keywords

  • FD-OCT, Flow measurement, Non-invasive, Oblique sample motion, Signal power decrease