The last decade has witnessed the blooming emergence of many-core platforms, especially the graphic processing units (GPUs). With the exponential growth of cores in GPUs, utilizing them efficiently becomes a challenge. The data-parallel programming model assumes a single instruction stream for multiple concurrent threads (SIMT); therefore little support is offered to enforce thread ordering and finegrained synchronizations. This becomes an obstacle when migrating algorithms which exploit fine-grained parallelism, to GPUs, such as the dataow algorithms. In this paper, we propose a novel approach for fine-grained inter-thread synchronizations on the shared memory of modern GPUs. We demonstrate its performance and compare it with other fine-grained and medium-grained synchronization approaches. Our method achieves 1.5x speedup over the warp-barrier based approach and 4.0x speedup over the atomic spin-lock based approach on average. To further explore the possibility of realizing fine-grained dataow algorithms on GPUs, we apply the proposed synchronization scheme to Needleman-Wunsch-a 2D wavefront application involving massive cross-loop data dependencies. Our implementation achieves 3.56x speedup over the atomic spin-lock implementation and 1.15x speedup over the conventional data-parallel implementation for a basic sub-grid, which implies that the fine-grained, lock-based programming pattern could be an alternative choice for designing general-purpose GPU applications (GPGPU).