Fe-Catalyzed reductive NO-bond cleavage-a route to the diastereoselective 1,4-aminohydroxylation of 1,3-dienes

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Contributors

  • S. Scholz - , University of Stuttgart (Author)
  • B. Plietker - , University of Stuttgart (Author)

Abstract

The low-valent Fe-complex Bu4N[Fe(CO)3(NO)] (TBA[Fe]) catalyzes the reductive cleavage of N-O-bonds in oxazines under salt-free conditions using malononitrile as reductant. The mild reduction conditions allow the development of a sequence of [4 + 2]-cycloaddition/reductive cleavage, a process that can be considered as an efficient way for the diastereoselective 1,4-aminohydroxylation of 1,3-dienes.

Details

Original languageEnglish
Pages (from-to)1295-1298
Number of pages4
JournalOrganic chemistry frontiers
Volume3
Issue number10
Publication statusPublished - Oct 2016
Peer-reviewedYes
Externally publishedYes

External IDs

ORCID /0000-0001-8423-6173/work/171062649

Keywords

ASJC Scopus subject areas