Feasibility, safety and efficacy of Woven EndoBridge embolization of intracranial aneurysms with the 2 mm height variants

Research output: Contribution to journal › Research article › Contributed › peer-review

Contributors

  • Lukas Goertz - , University of Cologne (Author)
  • Sophia Hohenstatt - , University Hospital Heidelberg (Author)
  • Eberhard Siebert - , Charité – Universitätsmedizin Berlin (Author)
  • Hanna Styczen - , University Hospital Essen (Author)
  • Alexander Ranft - , Klinikum Hochsauerland (Author)
  • David Zopfs - , University Hospital Aachen (Author)
  • Daniel Kaiser - , Institute and Polyclinic of Diagnostic and Interventional Neuroradiology, University Hospital Carl Gustav Carus Dresden (Author)
  • Pawel Krukowski - , Institute and Polyclinic of Diagnostic and Interventional Neuroradiology, University Hospital Carl Gustav Carus Dresden (Author)
  • Marc Schlamann - , University Hospital Aachen (Author)
  • Jonathan Kottlors - , University Hospital Aachen (Author)
  • Jan Paul Janssen - , University Hospital Aachen (Author)
  • Cornelius Deuschl - , University Hospital Essen (Author)
  • Franziska Dorn - , University of Bonn Medical Center (Author)
  • Markus A Möhlenbruch - , University Hospital Heidelberg (Author)
  • Thomas Liebig - , Hospital of the Ludwig-Maximilians-University (LMU) Munich (Author)
  • Christoph Kabbasch - , University Hospital Aachen (Author)

Abstract

PURPOSE: Small, shallow aneurysms (SSAs) present technical challenges for endovascular treatment with the risk of aneurysm perforation and coil protrusion. The Woven EndoBridge (WEB) device, particularly the lowest height of 2 mm variant, offers a potential alternative option for these aneurysms. This multicenter study evaluates the feasibility, safety and efficacy of the WEB for SSAs ≤ 4.1 mm width.

METHODS: A total of 103 aneurysms (mean size: 3.4 ± 1.1 mm, 67 [65%] bifurcation) treated with WEB single-layer sizes ranging from 3 × 2 mm to 4.5 × 2 mm were retrospectively analyzed. Data on procedural success, complications, and angiographic outcomes were collected. The incidence and potential strategies to counteract WEB protrusion were evaluated.

RESULTS: WEB deployment was successful in 97 (94%) cases, but WEB protrusion occurred in 12 (12%) cases. Strategies to counteract WEB protrusion were change to another endovascular technique (n = 4), additional stent implantation (n = 4), change to a smaller WEB size (n = 3), and repositioning of the WEB (n = 1). Procedural thromboembolic complications occurred in 4 (4%) cases, of which 3 were due to protrusion of the WEB, but all were asymptomatic. Two hemorrhagic complications (2%), caused by aneurysm perforation with the microwire in the first case and with the folded WEB tip in the second, resulted in procedural morbidity (2%). Complete and adequate occlusion rates were 82% (42/51) and 90% (46/51) at 6 months and 76% (19/25) and 88% (22/25) at 12 months, respectively.

CONCLUSION: The 2 mm height WEB demonstrated feasibility and efficacy in the treatment of SSAs with good safety results, making it a viable alternative endovascular option for SSAs.

Details

Original languageEnglish
Pages (from-to)3229-3238
Number of pages10
JournalNeuroradiology
Volume67
Issue number11
Publication statusE-pub ahead of print - 1 Nov 2025
Peer-reviewedYes

External IDs

Scopus 105020286125
ORCID /0000-0001-5258-0025/work/196691893

Keywords

Keywords

  • Endovascular, Intracranial aneurysm, Intrasaccular, Flow-disruption