FDG PET/MR in initial staging of sarcoma: Initial experience and comparison with conventional imaging

Research output: Contribution to journal › Research article › Contributed › peer-review

Contributors

  • Ivan Platzek - , Institute and Polyclinic of Diagnostic and Interventional Radiology (Author)
  • Bettina Beuthien-Baumann - , Department of Child and Adolescent Psychiatry and Psychotherapy (Author)
  • Georg Schramm - , Helmholtz-Zentrum Dresden-Rossendorf (Author)
  • Jens Maus - , Helmholtz-Zentrum Dresden-Rossendorf (Author)
  • Michael Laniado - , Department of Child and Adolescent Psychiatry and Psychotherapy (Author)
  • Jörg Kotzerke - , Department of Nuclear Medicine (Author)
  • Jörg van den Hoff - , Helmholtz-Zentrum Dresden-Rossendorf (Author)
  • Markus Schuler - , Department of Child and Adolescent Psychiatry and Psychotherapy (Author)

Abstract

OBJECTIVE: To assess the feasibility of positron emission tomography/magnetic resonance imaging (PET/MR) with 18F-fluordeoxyglucose (FDG) for initial staging of sarcoma.

MATERIALS AND METHODS: Twenty-nine patients with sarcoma were included in this study. Weighted kappa (κ) was used to assess the agreement between PET/MR and conventional imaging (CT and MR). The accuracy of PET/MR and conventional imaging for distant metastases was compared using receiver operating characteristic (ROC) analysis.

RESULTS: T and M stage were identical for PET/MR and conventional modalities in all patients (κ=1). N stage was identical for 28/29 patients (κ=0.65).

CONCLUSIONS: FDG PET/MR shows excellent agreement with the currently preferred imaging methods (CT and MR) in initial staging of sarcoma.

Details

Original languageEnglish
Pages (from-to)126-132
Number of pages7
JournalClinical Imaging
Volume42
Publication statusPublished - 2017
Peer-reviewedYes

External IDs

researchoutputwizard legacy.publication#79504
PubMed 27951459
Scopus 85002691977

Keywords

Keywords

  • Adolescent, Adult, Aged, Bone Neoplasms/diagnostic imaging, Female, Fluorodeoxyglucose F18, Humans, Magnetic Resonance Imaging/methods, Male, Middle Aged, Multimodal Imaging/methods, Neoplasm Staging, Positron-Emission Tomography/methods, Radiopharmaceuticals, Sarcoma/diagnostic imaging, Soft Tissue Neoplasms/diagnostic imaging, Tomography, X-Ray Computed/methods, Young Adult