Fatal hepatic necrosis after isoflurane anaesthesia
Research output: Contribution to journal › Research article › Contributed › peer-review
Contributors
Abstract
Several halogenated anaesthetic agents have been associated with hepatotoxicity. We report a case of fulminant, fatal hepatic necrosis after uneventful isoflurane anaesthesia in a patient without previous liver disease, who may have been sensitised by previous exposure to enflurane. Although no anti-trifluoroacetyl antibodies could be detected in the patient's serum, isoflurane hepatotoxicity seems very likely to be the reason for fulminant hepatic failure in this patient.
Details
Original language | English |
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Pages (from-to) | 892-895 |
Number of pages | 4 |
Journal | Anaesthesia |
Volume | 52 |
Issue number | 9 |
Publication status | Published - Sept 1997 |
Peer-reviewed | Yes |
Externally published | Yes |
External IDs
PubMed | 9349074 |
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Keywords
ASJC Scopus subject areas
Keywords
- Anaesthetics, volatile; isoflurane, Complications; death, Liver; toxicity