Expression of the forkhead transcription factor FOXP1 is associated with tumor grade and Ki67 expression in clear cell renal cell carcinoma
Research output: Contribution to journal › Research article › Contributed › peer-review
Contributors
Abstract
Expression of FOXP1 and Ki67 was immunohistochemically assessed on tissue microarrays of 129 cases of clear cell renal cell carcinomas. Overall and disease-specific survival correlated inversely with pT-category, grading and lymph node metastasis in (p < .05). Expression of FOXP1 correlated negatively with tumor grading (p = .02), but neither with pT-category nor with lymph node metastasis. Significant positive correlation was shown for Ki67 expression and tumor stage and lymph node metastasis (p < .05). The overall survival and the disease-specific survival correlated negatively with the Ki67 status (p < .05). FOXP1 expression negatively correlated with Ki67 expression in clear cell renal cell carcinomas (p = .036).
Details
| Original language | English |
|---|---|
| Pages (from-to) | 123-129 |
| Number of pages | 7 |
| Journal | Cancer Investigation |
| Volume | 29 |
| Issue number | 2 |
| Publication status | Published - Feb 2011 |
| Peer-reviewed | Yes |
External IDs
| PubMed | 21210727 |
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Keywords
Sustainable Development Goals
ASJC Scopus subject areas
Keywords
- Clear cell renal cell carcinoma, FOXP1, Ki67, Survival, Tumor grading