Exact on-lattice stochastic reaction-diffusion simulations using partial-propensity methods
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Contributors
Abstract
Stochastic reaction-diffusion systems frequently exhibit behavior that is not predicted by deterministic simulation models. Stochastic simulation methods, however, are computationally expensive. We present a more efficient stochastic reaction-diffusion simulation algorithm that samples realizations from the exact solution of the reaction-diffusion master equation. The present algorithm, called partial-propensity stochastic reaction-diffusion (PSRD) method, uses an on-lattice discretization of the reaction-diffusion system and relies on partial-propensity methods for computational efficiency. We describe the algorithm in detail, provide a theoretical analysis of its computational cost, and demonstrate its computational performance in benchmarks. We then illustrate the application of PSRD to two- and three-dimensional pattern-forming Gray-Scott systems, highlighting the role of intrinsic noise in these systems.
Details
Original language | English |
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Article number | 244103 |
Journal | Journal of Chemical Physics |
Volume | 135 |
Issue number | 24 |
Publication status | Published - 28 Dec 2011 |
Peer-reviewed | Yes |
Externally published | Yes |
External IDs
PubMed | 22225140 |
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ORCID | /0000-0003-4414-4340/work/159608306 |