Exact on-lattice stochastic reaction-diffusion simulations using partial-propensity methods

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

Abstract

Stochastic reaction-diffusion systems frequently exhibit behavior that is not predicted by deterministic simulation models. Stochastic simulation methods, however, are computationally expensive. We present a more efficient stochastic reaction-diffusion simulation algorithm that samples realizations from the exact solution of the reaction-diffusion master equation. The present algorithm, called partial-propensity stochastic reaction-diffusion (PSRD) method, uses an on-lattice discretization of the reaction-diffusion system and relies on partial-propensity methods for computational efficiency. We describe the algorithm in detail, provide a theoretical analysis of its computational cost, and demonstrate its computational performance in benchmarks. We then illustrate the application of PSRD to two- and three-dimensional pattern-forming Gray-Scott systems, highlighting the role of intrinsic noise in these systems.

Details

Original languageEnglish
Article number244103
JournalJournal of Chemical Physics
Volume135
Issue number24
Publication statusPublished - 28 Dec 2011
Peer-reviewedYes
Externally publishedYes

External IDs

PubMed 22225140
ORCID /0000-0003-4414-4340/work/159608306