Epidemiologische Daten und medizinische Versorgungssituation von Patienten mit chronischen Entzündungserkrankungen in Deutschland: Real-World-Evidenz zu Prävalenz, Erkrankungskombinationen, Versorgung

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Gabriela Riemekasten - , Universitätsklinikum Schleswig-Holstein - Campus Lübeck (Author)
  • Renate Schmelz - , Department of internal Medicine I, University Hospital Carl Gustav Carus Dresden (Author)
  • Knut Schäkel - , University Hospital Gießen and Marburg (Author)
  • Diamant Thaci - , University of Lübeck (Author)
  • Stefan Schreiber - , University Hospital Schleswig-Holstein Campus Kiel (Author)
  • Marit Röcken - , Cilag AG (Author)
  • Holger Bartz - , Cilag AG (Author)
  • Tina Ploner - , InGef - Institut für angewandte Gesundheitsforschung Berlin GmbH (Author)
  • Ximing Liao - , InGef - Institut für angewandte Gesundheitsforschung Berlin GmbH (Author)
  • Valeria Weber - , IGES Institut GmbH (Author)
  • Karina C Manz - , IGES Institut GmbH (Author)
  • Harald Burkhardt - , Fraunhofer Institute for Translational Medicine and Pharmacology (Author)
  • Jan Leipe - , Sektion Rheumatologie (Author)

Abstract

BACKGROUND: Chronic inflammatory diseases (immune-mediated inflammatory diseases, IMID) can overlap or occur simultaneously due to clinical similarities. The resulting utilization of heathcare structures has not yet been investigated across disciplines but is of potential importance for optimizing the treatment of patients with IMID.

AIM OF THE WORK: Analysis of epidemiological data including utilization of care services in patients with selected IMIDs: psoriasis, psoriatic arthritis (PsA), rheumatoid arthritis (RA), ankylosing spondylitis, ulcerative colitis, Crohn's disease and connective tissue disease.

MATERIAL AND METHODS: In a retrospective cross-sectional analysis based on health insurances accounting data with a sample of approximately 4 million insured persons, the prevalence of the abovementioned IMID and the frequency of IMID combinations were analyzed based on documented diagnoses (ICD-10 GM). The frequency of hospitalizations and utilization of outpatient physician contacts was recorded in predefined specialist disciplines (general medicine, dermatology, gastroenterology, rheumatology) and compared with an age-adjusted and gender-adjusted reference population.

RESULTS: A total of 188,440 patients had at least 1 of the IMID diagnoses analyzed (4.7%), with an age peak of 61-70 years. The highest prevalence was observed for psoriasis (1.85%), followed by rheumatoid arthritis (1.38%). Combinations with at least one other IMID were relatively common (29%), with this being most common in patients with psoriatic arthritis (82.9%, of which 68.2% had psoriasis), followed by ankylosing spondylitis (27.5%) and Crohn's disease (21.6%). Compared to the reference population, patients with IMID were hospitalized more often and more frequently utilized the outpatient disciplines.

DISCUSSION: The study results describe that IMIDs occur in combination and that the patients make comparatively more use of care structures of different disciplines. A multidisciplinary approach could increase the efficiency of care; an evaluation is still pending.

Translated title of the contribution
Epidemiological data and medical care situation of patients with chronic inflammatory diseases in Germany
Real-world evidence on prevalence, disease combinations, care

Details

Original languageGerman
Pages (from-to)578-586
Number of pages9
JournalZeitschrift fur Rheumatologie
Volume83
Issue number7
Early online date9 Dec 2023
Publication statusPublished - Sept 2024
Peer-reviewedYes

External IDs

Scopus 85178958682

Keywords

Keywords

  • Efficiency of care, Retrospective cross-sectional analysis, Multidisciplinary approach, Immune-mediated inflammatory diseases, Health insurances accounting data

Library keywords