Epicardial and endocardial surgical ablation of atrial fibrillation: outcomes from CASE-AF Registry

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Ivana Mitrovic - , Munich Municipal Hospital Bogenhausen (Author)
  • Edgar Eszlari - , Munich Municipal Hospital Bogenhausen (Author)
  • Adi Cvorak - , Munich Municipal Hospital Bogenhausen (Author)
  • Andreas Liebold - , Ulm University Medical Center (Author)
  • Ardawan Rastan - , University Hospital Gießen and Marburg (Author)
  • Herko Grubitzsch - , Charité – Universitätsmedizin Berlin (Author)
  • Michael Knaut - , Department of Cardiac Surgery (at Dresden Heart Centre), University Hospital Carl Gustav Carus Dresden (Author)
  • Theodor Fischlein - , Nuremberg Clinic (Author)
  • Taoufik Ouarrak - , Institute for Heart Attack Research, Ludwigshafen, Germany. (Author)
  • Jochen Senges - , Institute for Heart Attack Research, Ludwigshafen, Germany. (Author)
  • Thorsten Hanke - , Asklepios Hospital Harburg (Author)
  • Nicolas Doll - , Schüchtermann-Klinik (Author)
  • Walter Eichinger - , Munich Municipal Hospital Bogenhausen (Author)

Abstract

OBJECTIVES: The German CArdioSurgEry Atrial Fibrillation Registry is a prospective, multicentric registry analysing outcomes of patients undergoing surgical ablation for atrial fibrillation as concomitant or stand-alone procedures. This data sub-analysis of the German CArdioSurgEry Atrial Fibrillation Registry aims to describe the in-hospital and 1-year outcomes after concomitant surgical ablation, based on 2 different ablation approaches, epicardial and endocardial surgical ablation.

METHODS: Between January 2017 and April 2020, 17 German cardiosurgical units enrolled 763 consecutive patients after concomitant surgical ablation. In the epicardial group, 413 patients (54.1%), 95.6% underwent radiofrequency ablation. In the endocardial group, 350 patients (45.9%), 97.7% underwent cryoablation. 61.5% of patients in the epicardial group and 49.4% of patients in the endocardial group presenting with paroxysmal atrial fibrillation. Pre-, intra- and post-operative data were gathered.

RESULTS: Upon discharge, 32.3% (n = 109) of patients after epicardial surgical ablation and 24.0% (n = 72) of patients after endocardial surgical ablation showed recurrence of atrial fibrillation. The in-hospital mortality rate was low, 2.2% (n = 9) in the epicardial and 2.9% (n = 10) in the endocardial group. The overall 1-year procedural success rate was 58.4% in the epicardial and 62.2% in the endocardial group, with significant symptom improvement in both groups. The 1-year mortality rate was 7.7% (n = 30) in epicardial and 5.0% (n = 17) in the endocardial group.

CONCLUSIONS: Concomitant surgical ablation is safe and effective with significant improvement in patient symptoms and freedom from atrial fibrillation. Adequate cardiac rhythm monitoring should be prioritized for higher quality data acquisition.

Details

Original languageEnglish
Article numberivae123
JournalInterdisciplinary cardiovascular and thoracic surgery
Volume39
Issue number1
Publication statusPublished - 3 Jul 2024
Peer-reviewedYes

External IDs

PubMedCentral PMC11246162
Scopus 85198716280

Keywords

Keywords

  • Atrial fibrillation, Concomitant surgical ablation, Cryoablation, Radiofrequency