The works in this book stem from research presented during 11 workshops and a doctrol symposium which were organized in the frame of the International Conference on Enterprise Interoperability (I-ESA 2018). Most of the papers presented in this book originate from European or national research projects. One major goal of the I-ESA workshops is the exchange of knowledge to encourage an active debate of results between the presenters and the audience, which could inspire further research. The results of the discussions are reflected in the papers finalized after the conference and documented in the workshop reports. With the conference subtitle "Smart services and business impact of enterprise interoperability", the workshops elaborate results of research and industry transfer in the area of smart service-related technologies like next generation Internet, IoT, cloud-based platforms, artificial intelligence and advanced enterprise modeling for future manufacturing.