Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane

Research output: Contribution to journalResearch articleContributedpeer-review



An endoscopic optical coherence tomography (OCT) system with a wide field-of-view of 8 mm is presented, which combines the image capability of endoscopic imaging at the middle ear with the advantages of functional OCT imaging, allowing a morphological and functional assessment of the human tympanic membrane. The endoscopic tube has a diameter of 3.5 mm and contains gradient-index optics for simultaneous forward-viewing OCT and video endoscopy. The endoscope allows the three-dimensional visualization of nearly the entire tympanic membrane. In addition, the oscillation of the tympanic membrane is measured spatially resolved and in the frequency range between 500 Hz and 5 kHz with 125 Hz resolution, which is realized by phase-resolved Doppler OCT imaging during acoustical excitation with chirp signals. The applicability of the OCT system is demonstrated in vivo. Due to the fast image acquisition, structural and functional measurements are only slightly affected by motion artifacts.


Original languageEnglish
Article number031017
JournalJournal of biomedical optics
Issue number3
Publication statusPublished - 1 Mar 2019

External IDs

PubMed 30516037
ORCID /0000-0002-3061-0171/work/142241300
ORCID /0000-0002-8160-3000/work/142248330
ORCID /0000-0003-0554-2178/work/142249803
ORCID /0009-0008-7642-8608/work/142255306
ORCID /0000-0003-2292-5533/work/142256547
ORCID /0000-0003-3894-1175/work/148603699
ORCID /0000-0002-5256-1497/work/153110534



  • endoscopic imaging, optical coherence tomography, otolaryngology