Endoscopic optical coherence tomography at the middle ear diagnostics

Research output: Contribution to book/conference proceedings/anthology/reportConference contributionContributedpeer-review

Abstract

Optical coherence tomography (OCT) is a contactless and non-invasive imaging technique. Due to the high resolution of some 10 μm and the penetration depth of 1-2 mm in scattering tissue, OCT closes the gap between microscopy and sonography. Here, we present a GRIN-based endoscopic OCT (eOCT) system for middle ear diagnostics. EOCT combines the benefit of endoscopic imaging and the advantage of morphological and functional investigation of the tympanic membrane (TM). The eOCT system has a working distance of 10 mm, which results in a field-of-view of 10 mm. This allows a full three-dimensional visualization of the TM and surrounding tissue. In addition, the oscillation of the TM can be measured spatially resolved and in the frequency range between 500 Hz and 5000 Hz with 125 Hz resolution, which is realized by phase-resolved Doppler-OCT. First clinical results are demonstrated for one selected cases, a middle ear effusion.

Details

Original languageEnglish
Title of host publicationClinical and Preclinical Optical Diagnostics II
EditorsJ. Quincy Brown, Ton G. van Leeuwen
PublisherSPIE - The international society for optics and photonics, Bellingham
ISBN (electronic)9781510628397, 9781557528209
Publication statusPublished - 2019
Peer-reviewedYes

Publication series

SeriesProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11073
ISSN1605-7422
SeriesConference proceedings from OSA Publishing
VolumePart F142-ECBO 2019

Conference

TitleSPIE/OSA European Conference on Biomedical Optics 2019
Abbreviated titleECBO 2019
Duration23 - 25 June 2019
LocationICM - International Congress Center
CityMünchen
CountryGermany

External IDs

ORCID /0000-0002-3061-0171/work/142241302
ORCID /0000-0002-8160-3000/work/142248340
ORCID /0000-0003-0554-2178/work/142249816
ORCID /0009-0008-7642-8608/work/142255310
ORCID /0000-0003-2292-5533/work/142256556
Scopus 85073720208
ORCID /0000-0003-3894-1175/work/148603705
ORCID /0000-0002-5256-1497/work/153110539

Keywords

Keywords

  • Endoscopic optical coherenc tomography, Morphological and functional imaging, Otorhinolaryngology