Effects of curvature on epithelial tissue —Coordinated rotational movement and other spatiotemporal arrangements

Research output: Contribution to journalResearch articleContributedpeer-review

Abstract

Coordinated movements of epithelial tissue are linked with active matter processes. We here consider the influence of curvature on the spatiotemporal arrangements and the shapes of the cells. The cells are represented by a multiphase field model which is defined on the surface of a sphere. Besides the classical solid and liquid phases, which depend on the curvature of the sphere, on mechanical properties of the cells and the strength of activity, we identify a phase of global rotation. This rotation provides a coordinated cellular movement which can be linked to tissue morphogenesis. This investigation on a sphere is a first step to investigate the delicate interplay between topological constraints, geometric properties and collective motion. Besides the rotational state we also analyse positional defects, identify global nematic order and study the associated orientational defects.

Details

Original languageEnglish
Article number67002
JournalEurophysics letters
Volume138
Issue number6
Publication statusPublished - 7 Jul 2022
Peer-reviewedYes

External IDs

Scopus 85134763353

Keywords