Developing Cole-Cole model for Bacillus subtilis fermentation
Research output: Contribution to book/Conference proceedings/Anthology/Report › Chapter in book/Anthology/Report › Contributed › peer-review
Contributors
Abstract
During the fermentation of Bacillus Subtilis it is unperceivable to observe the formation of spores since, following the evolution of spores is time consuming due to various sampling and analytical procedures. Dielectric spectroscopy has shown promising results, where the measured permittivity is correlated with the cell concentration. Most of the existing works focus on determining cell concentration and not on the determination of spores. In this work, we develop a permittivity model for cells in the fermentation solution based on the Cole-Cole equations that can be used to detect the sporulation phase in future work. Utilizing the data from several fermentation runs of Bacillus Subtilis, a superposition hypothesis is proposed. In this hypothesis, the model equations from Cole and Cole (1941) are used and the theoretical permittivity response of the cells is calculated. As a first step, the Cole-Cole model is developed, and the modeled permittivity values are fitted to the measured data and the results are analyzed.
Details
| Original language | English |
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| Title of host publication | Proceedings 33rd European Symposium on Computer Aided Process Engineering |
| Publisher | Elsevier B.V. on behalf of KeAi Communications Co. Ltd. |
| Pages | 2711-2716 |
| Number of pages | 6 |
| Publication status | Published - Jan 2023 |
| Peer-reviewed | Yes |
Publication series
| Series | Computer aided chemical engineering |
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| Volume | 52 |
| ISSN | 1570-7946 |
External IDs
| ORCID | /0000-0001-5165-4459/work/174432574 |
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Keywords
Research priority areas of TU Dresden
DFG Classification of Subject Areas according to Review Boards
Subject groups, research areas, subject areas according to Destatis
Sustainable Development Goals
ASJC Scopus subject areas
Keywords
- Cole-Cole, Permittivity, Sporulation, Superposition