Data-informed imaging: How radiography and shape models support endoscopic OCT imaging of the middle ear

Research output: Contribution to book/conference proceedings/anthology/reportConference contributionContributedpeer-review


Endoscopic optical coherence tomography (OCT) enables the assessment of the eardrum and the middle ear in vivo. However, revealing the ossicles is often limited due to shadowing effects of preceding structures and the 3D impression is difficult to interpret. To compare the identified middle ear structures, OCT and cone-beam CT of a patient were spatially aligned and showed a good agreement in locating malleus and the promontory wall. As CT imaging uses ionizing radiation and is thus limited in application, we furthermore provide a concept how radiology can be utilized as a priori knowledge for OCT imaging. Therefore, a statistical shape model derived from µCT data of temporal bone specimens was fitted to in vivo OCT measurements, potentially providing a real-time augmentation of endoscopic OCT for middle ear diagnostics in the future.


Original languageEnglish
Title of host publicationImaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2023
EditorsBrian Jet-Fei Wong, Justus F. Ilgner
PublisherSPIE - The international society for optics and photonics, Bellingham
ISBN (electronic)9781510658134
Publication statusPublished - 2023

Publication series

SeriesProgress in Biomedical Optics and Imaging - Proceedings of SPIE


TitleImaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2023
Duration28 January 2023
CitySan Francisco
CountryUnited States of America

External IDs

ORCID /0009-0002-1419-8698/work/142246456
ORCID /0000-0002-8160-3000/work/142248355
ORCID /0000-0003-0554-2178/work/142249919
ORCID /0009-0008-7642-8608/work/142255328
ORCID /0000-0002-4590-1908/work/163293970



  • micro-computed tomography, middle ear, optical coherence tomography, ossicles, statistical shape model