Cutting edge imaging of human cochlea by industrial high resolution computed micro tomography

Research output: Contribution to book/conference proceedings/anthology/reportConference contributionContributedpeer-review

Contributors

  • Björn Fischer - , Fraunhofer Institute for Nondestructive Testing (Author)
  • Peter Krüger - , Fraunhofer Institute for Nondestructive Testing (Author)
  • Anton A. Poznyakovskiy - , TUD Dresden University of Technology, Department of Otorhinolaryngology, Head and Neck Surgery (Author)
  • Thomas Zahnert - , Department of Otorhinolaryngology, Head and Neck Surgery (Author)

Abstract

Validation of statistically confirmed geometrical models of the human inner ear requires precise image data of bony structures and soft tissue. By optimization and application of our Industrial High Resolution Micro Computer Tomograph (microCT, Fraunhofer IZFP), we achieve an image quality known so far only from synchrotron X-ray tomography. To improve the generation of X-ray photons, the micro focus X-ray tube was equipped with a high performance transmission target with diamond carrier to achieve a higher photon flux at the same focal diameter. Additionally, our new alignment tool allows post-acquisition correction of adjustment incorrectness which plays a key role in reconstruction of high resolution microCT-data. However, an accurate segmentation of the cochlea is still problematic due to the low X-ray absorption contrast of the inner membranes of scalae. To solve this problem, the soft tissue was stained by putting the specimen into an iodine solution. The resulting data are of outstanding quality and provide the basin for an extensive anatomical study and further development of statistical geometrical models of the human inner ear.

Details

Original languageEnglish
Title of host publicationMedical Imaging 2012
Publication statusPublished - 2012
Peer-reviewedYes

Publication series

SeriesProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8313
ISSN1605-7422

Conference

TitleMedical Imaging 2012: Physics of Medical Imaging
Duration5 - 8 February 2012
CitySan Diego
CountryUnited States of America

External IDs

ORCID /0000-0003-3894-1175/work/148603852

Keywords

Keywords

  • atlas-based segmentation, CI, Diamond X-Ray Transmission Target, microCT, post-acquisition collection correction, staining of soft tissue, X-ray absorption contrast