Cutting edge imaging of human cochlea by industrial high resolution computed micro tomography
Research output: Contribution to book/conference proceedings/anthology/report › Conference contribution › Contributed › peer-review
Contributors
Abstract
Validation of statistically confirmed geometrical models of the human inner ear requires precise image data of bony structures and soft tissue. By optimization and application of our Industrial High Resolution Micro Computer Tomograph (microCT, Fraunhofer IZFP), we achieve an image quality known so far only from synchrotron X-ray tomography. To improve the generation of X-ray photons, the micro focus X-ray tube was equipped with a high performance transmission target with diamond carrier to achieve a higher photon flux at the same focal diameter. Additionally, our new alignment tool allows post-acquisition correction of adjustment incorrectness which plays a key role in reconstruction of high resolution microCT-data. However, an accurate segmentation of the cochlea is still problematic due to the low X-ray absorption contrast of the inner membranes of scalae. To solve this problem, the soft tissue was stained by putting the specimen into an iodine solution. The resulting data are of outstanding quality and provide the basin for an extensive anatomical study and further development of statistical geometrical models of the human inner ear.
Details
Original language | English |
---|---|
Title of host publication | Medical Imaging 2012 |
Publication status | Published - 2012 |
Peer-reviewed | Yes |
Publication series
Series | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
---|---|
Volume | 8313 |
ISSN | 1605-7422 |
Conference
Title | Medical Imaging 2012: Physics of Medical Imaging |
---|---|
Duration | 5 - 8 February 2012 |
City | San Diego |
Country | United States of America |
External IDs
ORCID | /0000-0003-3894-1175/work/148603852 |
---|
Keywords
ASJC Scopus subject areas
Keywords
- atlas-based segmentation, CI, Diamond X-Ray Transmission Target, microCT, post-acquisition collection correction, staining of soft tissue, X-ray absorption contrast