Criteria for the standardization of stem-cell-based embryo models

Research output: Contribution to journalComment/debateContributedpeer-review

Contributors

  • Alfonso Martinez Arias - , Pompeu Fabra University (Author)
  • Nicolas Rivron - , Institute of Molecular Biotechnology (IMBA) (Author)
  • Naomi Moris - , The Francis Crick Institute (Author)
  • Patrick Tam - , University of Sydney (Author)
  • Cantas Alev - , Kyoto University (Author)
  • Jianping Fu - , University of Michigan, Ann Arbor (Author)
  • Anna Katerina Hadjantonakis - , Memorial Sloan-Kettering Cancer Center (Author)
  • Jacob H. Hanna - , Weizmann Institute of Science (Author)
  • Gabriella Minchiotti - , National Research Council of Italy (CNR) (Author)
  • Olivier Pourquie - , Harvard University (Author)
  • Guojun Sheng - , Kumamoto University (Author)
  • Liliana Solnica Krezel - , Washington University St. Louis (Author)
  • Jesse V. Veenvliet - , Max Planck Institute of Molecular Cell Biology and Genetics, TUD Dresden University of Technology, Center for Systems Biology Dresden (CSBD), Clusters of Excellence PoL: Physics of Life (Author)
  • Aryeh Warmflash - , Rice University (Author)

Abstract

Pluripotent stem cells are being used to generate models of early embryogenesis that are promising for discovery and translational research. To be useful, these models require critical consideration of their level of efficiency and fidelity to natural embryos. Here we propose criteria with which to raise the standards of stem-cell-based embryo models of human embryogenesis.

Details

Original languageEnglish
Number of pages4
JournalNature cell biology
Volume26
Issue number10
Publication statusAccepted/In press - 2024
Peer-reviewedYes

Keywords

ASJC Scopus subject areas