This text structures the application of Wire-Mesh sensors and Electrical Resistance Tomography in the control of an Inline Swirl Separator. It introduces a mechanistic model of the two-phase flow inside the device, which is linearized around an ideal perfect operation, and implemented in a Model Predictive Controller. The whole text is structured aiming at a future real application of the controller, briefly introducing the setup that is going to be used, the sensors and their working principles. The results obtained show a stable controller, able to regulate the process relatively fast in relation to the time resolution of the sensors. The positive response of the approach stimulates further improvements in the model developed, and the implementation of more sophisticated techniques to handle the non-linearities of the process.