Concept paper on the technique of cryopreservation, removal and transplantation of ovarian tissue for fertility preservation

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Matthias W. Beckmann - , Friedrich-Alexander University Erlangen-Nürnberg (Author)
  • Laura Lotz - , Friedrich-Alexander University Erlangen-Nürnberg (Author)
  • Bettina Toth - , Innsbruck Medical University (Author)
  • Dunja Maria Baston-Büst - , University Hospital Duesseldorf (Author)
  • Tanja Fehm - , University Hospital Duesseldorf (Author)
  • Torsten Frambach - , University of Göttingen (Author)
  • Ariane Germeyer - , Heidelberg University  (Author)
  • Maren Goeckenjan - , Department of Gynecology and Obstetrics (Author)
  • Felix Häberlin - , Cantonal Hospital St. Gallen (Author)
  • Melanie Henes - , University of Tübingen (Author)
  • Jens Hirchenhain - , University Hospital Duesseldorf (Author)
  • Stephanie Hübner - , University of Tübingen (Author)
  • Matthias Korell - , Johanna Etienne Hospital (Author)
  • Jan Steffen Krüssel - , University Hospital Duesseldorf (Author)
  • Andreas Müller - , Städtischen Klinikum Karlsruhe (Author)
  • Jochen Reinsberg - , University of Bonn (Author)
  • Roxana Schwab - , Johannes Gutenberg University Mainz (Author)
  • Stephan Seitz - , University of Regensburg (Author)
  • Marc Sütterlin - , Heidelberg University  (Author)
  • Hans Van Der Ven - , University of Bonn (Author)
  • Katrin Van Der Ven - , University of Bonn (Author)
  • Katharina Winkler-Crepaz - , Innsbruck Medical University (Author)
  • Pauline Wimberger - , Department of Gynecology and Obstetrics (Author)
  • Michael Von Wolff - , University of Bern (Author)
  • Jana Liebenthron - , University Hospital Duesseldorf (Author)
  • Ralf Dittrich - , Friedrich-Alexander University Erlangen-Nürnberg (Author)

Abstract

The cryopreservation of ovarian tissue with subsequent transplantation of the tissue represents an established method of fertility protection for female patients who have to undergo gonadotoxic therapy. The procedure can be performed at any point in the cycle and thus generally does not lead to any delay in oncological therapy. With the aid of this procedure, more than 130 births to date worldwide have been able to be recorded. The birth rate is currently approximately 30% and it can be assumed that this will increase through the further optimisation of the cryopreservation and surgical technique. The concept paper presented here is intended to provide guidance for managing cryopreservation and transplantation of ovarian tissue to German-speaking reproductive medicine centres.

Details

Original languageEnglish
Pages (from-to)53-62
Number of pages10
JournalGeburtshilfe und Frauenheilkunde
Volume79
Issue number1
Publication statusPublished - 2019
Peer-reviewedYes

Keywords

Keywords

  • Cryopreservation, Fertility protection, FertiPROTEKT, Ovarian tissue, Transplantation

Library keywords