Comparison of LSO and BGO block detectors for prompt gamma imaging in ion beam therapy

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • F. Hueso-González - , University Hospital Carl Gustav Carus Dresden, Helmholtz-Zentrum Dresden-Rossendorf, OncoRay - National Centre for Radiation Research in Oncology (Author)
  • A. K. Biegun - , University of Groningen (Author)
  • P. Dendooven - , University of Groningen (Author)
  • W. Enghardt - , OncoRay - National Center for Radiation Research in Oncology, University Hospital Carl Gustav Carus Dresden, Helmholtz-Zentrum Dresden-Rossendorf (Author)
  • F. Fiedler - , Helmholtz-Zentrum Dresden-Rossendorf (Author)
  • C. Golnik - , OncoRay - National Center for Radiation Research in Oncology, University Hospital Carl Gustav Carus Dresden (Author)
  • K. Heidel - , Helmholtz-Zentrum Dresden-Rossendorf (Author)
  • T. Kormoll - , OncoRay - National Center for Radiation Research in Oncology, University Hospital Carl Gustav Carus Dresden (Author)
  • J. Petzoldt - , University Hospital Carl Gustav Carus Dresden, OncoRay - National Centre for Radiation Research in Oncology (Author)
  • K. E. Römer - , University Hospital Carl Gustav Carus Dresden, OncoRay - National Centre for Radiation Research in Oncology (Author)
  • R. Schwengner - , Helmholtz-Zentrum Dresden-Rossendorf (Author)
  • A. Wagner - , Helmholtz-Zentrum Dresden-Rossendorf (Author)
  • G. Pausch - , University Hospital Carl Gustav Carus Dresden, OncoRay - National Centre for Radiation Research in Oncology (Author)

Abstract

A major weakness of ion beam therapy is the lack of tools for verifying the particle range in clinical routine. The application of the Compton camera concept for the imaging of prompt gamma rays, a by-product of the irradiation correlated to the dose distribution, is a promising approach for range assessment and even three-dimensional in vivo dosimetry. Multiple position sensitive gamma ray detectors arranged in scatter and absorber planes, together with an imaging algorithm, are required to reconstruct the prompt gamma emission density map. Conventional block detectors deployed in Positron Emission Tomography (PET), which are based on Lu2SiO5:Ce (LSO) and Bi4Ge3O12 (BGO) scintillators, are suitable candidates for the absorber of a Compton camera due to their high density and absorption efficiency with respect to the prompt gamma energy range (several MeV). We compare experimentally LSO and BGO block detectors in clinical-like radiation fields in terms of energy, spatial and time resolution. The high energy range compensates for the low light yield of the BGO material and boosts significantly its performance compared to the PET scenario. Notwithstanding the overall superiority of LSO, BGO catches up in the field of prompt gamma imaging and can be considered as a competitive alternative to LSO for the absorber plane due to its lower price and the lack of intrinsic radioactivity.

Details

Original languageEnglish
Article numberP09015
JournalJournal of instrumentation
Volume10
Issue number9
Publication statusPublished - 14 Sept 2015
Peer-reviewedYes

External IDs

ORCID /0000-0001-9023-3606/work/167708033

Keywords

ASJC Scopus subject areas

Keywords

  • Compton imaging; Gamma detectors (scintillators, CZT, etc), HgI etc); Detector modelling and simulations I (interaction of radiation with matter, HPG, interaction of hadrons with matter, interaction of photons with matter