Cohesin in determining chromosome architecture
Research output: Contribution to journal › Review article › Contributed › peer-review
Contributors
Abstract
Cells use ring-like structured protein complexes for various tasks in DNA dynamics. The tripartite cohesin ring is particularly suited to determine chromosome architecture, for it is large and dynamic, may acquire different forms, and is involved in several distinct nuclear processes. This review focuses on cohesin's role in structuring chromosomes during mitotic and meiotic cell divisions and during interphase.
Details
Original language | English |
---|---|
Pages (from-to) | 1386-1393 |
Number of pages | 8 |
Journal | Experimental Cell Research |
Volume | 318 |
Issue number | 12 |
Publication status | Published - 15 Jul 2012 |
Peer-reviewed | Yes |
External IDs
Scopus | 84861949299 |
---|---|
PubMed | 22472347 |
Keywords
Keywords
- Animals, Cell Cycle Proteins/genetics, Cell Nucleus/genetics, Chromosomal Proteins, Non-Histone/genetics, Chromosomes/chemistry, Humans, Interphase/genetics, Meiosis/genetics, Mitosis/genetics, Models, Biological, Nucleic Acid Conformation, Sister Chromatid Exchange/genetics