Coalescence of liquid or gel-like DNA-encapsulating microdroplets

Research output: Contribution to journalResearch articleContributedpeer-review

Abstract

Liquid-liquid phase separation plays a prominent role in the physics of life, providing the cells with various membrane-less compartments. These structures exhibit a range of material properties that, in many cases, change over time. Inspired by this, we investigate here an aqueous two-phase system formed by mixing polyethylene glycol with dextran. We modulate the material properties of the resulting dextran droplets by adding DNA that readily enters the droplets. We find a non-monotonic dependence of the physical properties of the droplets under the imposed ionic conditions.

Details

Original languageEnglish
Article number134904
JournalJournal of Chemical Physics
Volume161
Issue number13
Publication statusPublished - 7 Oct 2024
Peer-reviewedYes

External IDs

PubMed 39356067
ORCID /0000-0001-8761-1776/work/169643746