The Supreme Court’s June 2026 ruling in Trump v. Slaughter may affect how U.S. clinical trial sponsors receive long-term safety data from Europe. The ruling invalidated statutory removal protections for Federal Trade Commission (FTC) commissioners. That matters for the EU-U.S. Data Privacy Framework (DPF), which allows personal data transfers from the EU to eligible, certified U.S. organizations. The FTC enforces participating companies’ privacy commitments, and the European Commission expressly relied on protections for the FTC’s independence when approving the framework. The DPF remains in force, but European regulators are examining whether U.S. protections still meet EU standards given the changes from Trump v. Slaughter.