Chitinous scaffolds from marine sponges for tissue engineering

Research output: Contribution to book/Conference proceedings/Anthology/ReportChapter in book/Anthology/ReportContributedpeer-review

Contributors

  • Vitalii Mutsenko - , Leibniz University Hannover (LUH) (Author)
  • Oleksandr Gryshkov - , Leibniz University Hannover (LUH) (Author)
  • Olena Rogulska - , NASU - Institute for Problems of Cryobiology and Cryomedicine (Author)
  • Anja Lode - , Centre for Translational Bone, Joint and Soft Tissue Research (Author)
  • Alexander Yu Petrenko - , NASU - Institute for Problems of Cryobiology and Cryomedicine (Author)
  • Michael Gelinsky - , Centre for Translational Bone, Joint and Soft Tissue Research (Author)
  • Birgit Glasmacher - , Leibniz University Hannover (LUH) (Author)
  • Hermann Ehrlich - , Freiberg University of Mining and Technology (Author)

Abstract

Chitin as a biological material which has been identified in skeletal structures of a broad variety of unicellular (yeast, protists, diatoms) and multicellular (sponges, corals, worms, molluscs, arthropods) organisms is recognized as natural template with good perspectives in modern biomedicine. This chapter provides first insights into prospective applications of naturally prefabricated three-dimensional chitinous scaffolds from selected marine sponges in tissue engineering. This became possible only owing to the recent discovery of poriferan chitin which provoked renewed multidisciplinary interest driven by growing demand in novel biomimetic materials. Here, we focused on both demosponges of Verongiida order as a renewable source of chitin scaffolds with jewelry designs, and human mesenchymal stromal cells having high therapeutic potential. The chapter covers approaches for isolation of scaffolds from the chitin-bearing marine sponges, nuances of their interaction with human cells and cryopreservation potential.

Details

Original languageEnglish
Title of host publicationSpringer Series in Biomaterials Science and Engineering
PublisherSpringer Science and Business Media, LLC
Pages285-307
Number of pages23
Publication statusPublished - 2019
Peer-reviewedYes

Publication series

SeriesSpringer Series in Biomaterials Science and Engineering
Volume14
ISSN2195-0644

External IDs

ORCID /0000-0001-9075-5121/work/160047965

Keywords

Sustainable Development Goals

ASJC Scopus subject areas

Keywords

  • Biomimetic approaches, Chitin, Chitinous scaffolds, Cryopreservation, Cytocompatibility, Marine sponges, Stem cells, Tissue engineering