Cellular motors for molecular manufacturing

Research output: Contribution to journalReview articleContributedpeer-review

Contributors

  • C. Z. Dinu - , Max Planck Institute of Molecular Cell Biology and Genetics, Rensselaer Polytechnic Institute (Author)
  • D. B. Chrisey - , Rensselaer Polytechnic Institute (Author)
  • S. Diez - , Max Planck Institute of Molecular Cell Biology and Genetics (Author)
  • J. Howard - , Max Planck Institute of Molecular Cell Biology and Genetics (Author)

Abstract

Cells are composed of macromolecular structures of various sizes that act individually or collectively to maintain their viability and perform their function within the organism. This review focuses on one structure, the microtubule, and one of the motor proteins that move along it, conventional kinesin (kinesin 1). Recent work on the cellular functions of kinesins, such as the organization of microtubules during cellular division and the movement of the organelles and vesicles, offers insights into how biological motors might prove useful for organizing structures in engineered environments.

Details

Original languageEnglish
Pages (from-to)1203-1212
Number of pages10
Journal The anatomical record : AR ; advances in integrative anatomy and evolutionary biology ; an official publication of the American Association of Anatomists, AAA
Volume290
Issue number10
Publication statusPublished - Oct 2007
Peer-reviewedYes
Externally publishedYes

External IDs

PubMed 17847054
ORCID /0000-0002-0750-8515/work/142235593

Keywords

Research priority areas of TU Dresden

Keywords

  • DNA, Kinesin, Microtubule, Molecular manufacturing