CD133 and membrane microdomains: old facets for future hypotheses.

Research output: Contribution to journalResearch articleContributedpeer-review


Understanding all facets of membrane microdomains in normal and cancerous cells within the digestive tract is highly important, not only from a clinical point of view, but also in terms of our basic knowledge of cellular transformation. By studying the normal and cancer stem cell-associated molecule CD133 (prominin-1), novel aspects of the organization and dynamics of polarized epithelial cells have been revealed during the last decade. Its association with particular membrane microdomains is highly relevant in these contexts and might also offer new avenues in diagnosis and/or targeting of cancer stem cells.


Original languageEnglish
Pages (from-to)4149-4152
JournalWorld journal of gastroenterology : WJG ; a weekly journal of gastroenterology and hepatology
Publication statusPublished - Sept 2011

External IDs

PubMed 22039332
PubMed PMC3203369
Scopus 80155181523
ORCID /0000-0001-7687-0983/work/142253722


Sustainable Development Goals