Blood flow measurement in the in vivo mouse model by the combination of Doppler OCT and the signal power decrease in spectral domain OCT

Research output: Contribution to book/conference proceedings/anthology/reportConference contributionContributedpeer-review

Abstract

Blood flow measurement with spectrometer-based Fourier domain optical coherence tomography (FD OCT) is limited by the motion-induced signal fading and the resulting reduction of flow sensitivity. In this study, a combination of the established Doppler OCT and the numerically simulated signal damping due to obliquely moved scatterers is used to estimate the systolic blood flow velocities in the in vivo mouse model at which the standard Doppler OCT does not work any longer.

Details

Original languageEnglish
Title of host publicationOptical Coherence Tomography and Coherence Techniques IV
Publication statusPublished - 2009
Peer-reviewedYes

Publication series

SeriesProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7372
ISSN1605-7422

Conference

TitleOptical Coherence Tomography and Coherence Techniques IV
Duration14 - 17 June 2009
CityMunich
CountryGermany

External IDs

Scopus 79959349289
ORCID /0000-0003-0554-2178/work/142249870
ORCID /0000-0003-2292-5533/work/142256608
ORCID /0000-0001-9360-9736/work/164198449

Keywords

Keywords

  • Blood flow, Doppler, Fourier domain optical coherence tomography, In vivo mouse model, Oblique sample motion, Signal damping