Bicyclic selenenyl sulfides tune stepwise rates of thiol/selenol addition, resolution, and cyclisation, to reveal cellular constraints for bioreductive probes targeting mammalian thioredoxin reductase

Research output: Preprint/Documentation/Report › Preprint

Contributors

  • Lukas Zeisel - , Chair of Organic Chemistry II, Ludwig Maximilian University of Munich (Author)
  • Lucas Dessen-Weissenhorn - , Ludwig Maximilian University of Munich (Author)
  • Karoline C. Scholzen - , Karolinska Institutet (Author)
  • Andrea Madabeni - , University of Padua (Author)
  • Laura Orian - , University of Padua (Author)
  • Elias S. J. Arnér - , Karolinska Institutet (Author)
  • Oliver Thorn-Seshold - , Chair of Organic Chemistry II (Author)

Details

Original languageEnglish
Publication statusPublished - 25 Feb 2025
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Keywords

Research priority areas of TU Dresden

DFG Classification of Subject Areas according to Review Boards