Atypical laterality of resting gamma oscillations in autism spectrum disorders
Research output: Contribution to journal › Research article › Contributed › peer-review
Contributors
Abstract
Abnormal brain oscillatory activity has been found in autism spectrum disorders (ASD) and proposed as a potential biomarker. While several studies have investigated gamma oscillations in ASD, none have examined resting gamma power across multiple brain regions. This study investigated resting gamma power using EEG in 15 boys with ASD and 18 age and intelligence quotient matched typically developing controls. We found a decrease in resting gamma power at right lateral electrodes in ASD. We further explored associations between gamma and ASD severity as measured by the Social Responsiveness Scale (SRS) and found a negative correlation between SRS and gamma power. We believe that our findings give further support of gamma oscillations as a potential biomarker for ASD.
Details
Original language | English |
---|---|
Pages (from-to) | 292-7 |
Number of pages | 6 |
Journal | Journal of autism and developmental disorders |
Volume | 45 |
Issue number | 2 |
Publication status | Published - Feb 2015 |
Peer-reviewed | Yes |
External IDs
PubMedCentral | PMC6102725 |
---|---|
Scopus | 84876666251 |
Keywords
Keywords
- Adolescent, Brain/physiology, Case-Control Studies, Child Development Disorders, Pervasive/physiopathology, Electroencephalography, Functional Laterality/physiology, Gamma Rhythm/physiology, Humans, Male, Rest