Asymmetric reduction of ketones with recombinant E. coli whole cells in neat substrates

Research output: Contribution to journal › Research article › Contributed › peer-review

Contributors

  • Andre Jakoblinnert - , RWTH Aachen University (First author)
  • Radost Mladenov - (Author)
  • Andreas Paul - (Author)
  • Fabrizio Sibilla - (Author)
  • Ulrich Schwaneberg - (Author)
  • Marion Bettina Ansorge-Schumacher - , Technical University of Berlin (Author)

Abstract

The asymmetric reduction of ketones is performed by using lyophilized whole cells in neat substrates with defined water activity (aw). Ketones and alcohols prone to be unstable in aqueous media can now be converted via biocatalysis.

Details

Original languageEnglish
Pages (from-to)12230-12232
JournalChemical Communications
Volume2011
Issue number47
Publication statusPublished - 2011
Peer-reviewedYes
Externally publishedYes

External IDs

Scopus 80155198142
ORCID /0000-0002-2912-546X/work/171551887

Keywords

Keywords

  • Asymmetrische Synthese, Carbonylreduktase, Biokatalyse, Ganzzellbiotransformation