Advances in the prevention, management, and treatment of community-acquired pneumonia

Research output: Contribution to journalReview articleContributedpeer-review

Contributors

  • Mathias W Pletz - , Jena University Hospital (Author)
  • Gernot G Rohde - , Leibniz University Hannover (LUH) (Author)
  • Tobias Welte - , Maastricht University (Author)
  • Martin Kolditz - , Department of internal Medicine I, Division of Pulmonology, University Hospital Carl Gustav Carus Dresden (Author)
  • Sebastian Ott - , University Hospital Münster (Author)

Abstract

Community-acquired pneumonia (CAP) is the infectious disease with the highest number of deaths worldwide. Nevertheless, its importance is often underestimated. Large cohorts of patients with CAP have been established worldwide and improved our knowledge about CAP by far. Therefore, current guidelines are much more evidence-based than ever before. This article discusses recent major studies and concepts on CAP such as the role of biomarkers, appropriate risk stratification to identify patients in need of hospitalisation or intensive care, appropriate empiric antibiotic therapy (including the impact of macrolide combination therapy and antibiotic stewardship), and CAP prevention with novel influenza and pneumococcal vaccines.

Details

Original languageEnglish
JournalF1000Research
Volume5
Publication statusPublished - 2016
Peer-reviewedYes

External IDs

PubMed 26998243
PubMedCentral PMC4786904
Scopus 84964645052
ORCID /0000-0001-6022-6827/work/142659558

Keywords

Sustainable Development Goals