Acute effects of caffeine on heart rate variability in habitual caffeine consumers

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Robert Rauh - , Friedrich-Alexander University Erlangen-Nürnberg (Author)
  • Michaela Burkert - , Friedrich-Alexander University Erlangen-Nürnberg (Author)
  • Martin Siepmann - , Institute of Clinical Pharmacology (Author)
  • Michael Mueck-Weymann - , Department of Psychotherapy and Psychosomatic Medicine (Author)

Abstract

During the last years, heart rate variability (HRV) has become a promising risk factor for cardiovascular events. However, the effect of caffeine on HRV in habitual caffeine consumers has barely been investigated. Therefore, we treated 30 male habitual caffeine users in a randomized double-blinded crossover study design with either placebo, 100 or 200 mg caffeine orally and determined parameters of HRV under resting conditions and metronomic breathing. As result, we could not detect significant differences in HRV parameters up to 90 min after drug ingestion. We conclude that modest amounts of caffeine do not reveal negative nor positive effects on HRV within the first 90 min after drug ingestion in young and healthy habitual caffeine consumers. However, further research is necessary to determine the effects of caffeine on HRV in habitual caffeine users, healthy as well as suffering from diabetes, hypertension and postmyocardial infarction.

Details

Original languageEnglish
Pages (from-to)163-166
Number of pages4
JournalClinical physiology and functional imaging
Volume26
Issue number3
Publication statusPublished - May 2006
Peer-reviewedYes

External IDs

PubMed 16640511

Keywords

Sustainable Development Goals

ASJC Scopus subject areas

Keywords

  • Autonomic nervous system, Double-blind method, Human experimentation, Physiological effects of caffeine