A novel technique for olfactory bulb measurements

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

Abstract

BACKGROUND: To introduce new ways to calculate OB volumes, checking their validity and comparing them to already established technique i.e. OB volumetric based on manual segmentation of OB boundaries.

METHODS: Two approaches were used to calculate OB volumes (1) Manual Segmentation using planimetric manual contouring; (2) Box-frame method, calculating the parameters based on a box placed around the OB.

RESULTS: We calculated OB volumes using both techniques and found comparable outcomes. High inter-observer reliability was found for volumes calculated by both observers. For manual segmentation, Cronbach's alpha (α) was 0.91 and 0.93 for right and left OB volume, respectively, whereas for the box-frame method α was 0.94 and 0.90 for right and left OB, respectively.

CONCLUSIONS: The simple box-frame method of OB volume calculation appears reliable. Its results are comparable to an established technique.

Details

Original languageEnglish
Pages (from-to)e0243941
JournalPloS one
Volume15
Issue number12
Publication statusPublished - 2020
Peer-reviewedYes

External IDs

PubMedCentral PMC7743925
Scopus 85098253544
ORCID /0000-0001-9713-0183/work/146645319

Keywords

Keywords

  • Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Olfactory Bulb/anatomy & histology, Organ Size/physiology, Smell/physiology