A novel mechanism of cochlear excitation during simultaneous stimulation and pressure relief through the round window

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Thomas D Weddell - , University of Brighton (Author)
  • Yury M Yarin - , Department of Otorhinolaryngology, Head and Neck Surgery (Author)
  • Markus Drexl - (Author)
  • Ian J Russell - (Author)
  • Stephen J Elliott - (Author)
  • Andrei N Lukashkin - (Author)

Abstract

The round window (RW) membrane provides pressure relief when the cochlea is excited by sound. Here, we report measurements of cochlear function from guinea pigs when the cochlea was stimulated at acoustic frequencies by movements of a miniature magnet which partially occluded the RW. Maximum cochlear sensitivity, corresponding to subnanometre magnet displacements at neural thresholds, was observed for frequencies around 20 kHz, which is similar to that for acoustic stimulation. Neural response latencies to acoustic and RW stimulation were similar and taken to indicate that both means of stimulation resulted in the generation of conventional travelling waves along the cochlear partition. It was concluded that the relatively high impedance of the ossicles, as seen from the cochlea, enabled the region of the RW not occluded by the magnet, to act as a pressure shunt during RW stimulation. We propose that travelling waves, similar to those owing to acoustic far-field pressure changes, are driven by a jet-like, near-field component of a complex pressure field, which is generated by the magnetically vibrated RW. Outcomes of research described here are theoretical and practical design principles for the development of new types of hearing aids, which use near-field, RW excitation of the cochlea.

Details

Original languageEnglish
Pages (from-to)20131120
JournalJournal of the Royal Society Interface
Volume11
Issue number93
Publication statusPublished - 6 Apr 2014
Peer-reviewedYes
Externally publishedYes

External IDs

PubMedCentral PMC3928943
Scopus 84896945648

Keywords

Sustainable Development Goals

Keywords

  • Acoustic Stimulation, Animals, Cochlea/anatomy & histology, Guinea Pigs, Hearing Aids, Pressure