A methodology for in silico endovascular repair of abdominal aortic aneurysms
Research output: Contribution to journal › Research article › Contributed › peer-review
Contributors
Abstract
Endovascular aneurysm repair (EVAR) can involve some unfavorable complications such as endoleaks or stent-graft (SG) migration. Such complications, resulting from the complex mechanical interaction of vascular tissue, SG and blood flow or incompatibility of SG design and vessel geometry, are difficult to predict. Computational vascular mechanics models can be a predictive tool for the selection, sizing and placement process of SGs depending on the patient-specific vessel geometry and hence reduce the risk of potential complications after EVAR. In this contribution, we present a new in silico EVAR methodology to predict the final state of the deployed SG after intervention and evaluate the mechanical state of vessel and SG, such as contact forces and wall stresses. A novel method to account for residual strains and stresses in SGs, resulting from the precompression of stents during the assembly process of SGs, is presented. We suggest a parameter continuation approach to model various different sizes of SGs within one in silico EVAR simulation which can be a valuable tool when investigating the issue of SG oversizing. The applicability and robustness of the proposed methods are demonstrated on the example of a synthetic abdominal aortic aneurysm geometry.
Details
Original language | English |
---|---|
Pages (from-to) | 1139-1164 |
Number of pages | 26 |
Journal | Biomechanics and modeling in mechanobiology |
Volume | 17 |
Issue number | 4 |
Publication status | Published - 1 Aug 2018 |
Peer-reviewed | Yes |
External IDs
PubMed | 29752606 |
---|
Keywords
ASJC Scopus subject areas
Keywords
- Abdominal aortic aneurysm, Endovascular aneurysm repair, Finite element method, Oversizing, Stent-graft