A definition of bioinks and their distinction from biomaterial inks

Research output: Contribution to journalReview articleContributedpeer-review

Contributors

  • J. Groll - , University of Würzburg (Author)
  • J. A. Burdick - , University of Pennsylvania (Author)
  • D. W. Cho - , Center for Rapid Prototyping (Author)
  • B. Derby - , University of Manchester (Author)
  • M. Gelinsky - , Centre for Translational Bone, Joint and Soft Tissue Research (Author)
  • S. C. Heilshorn - , Stanford Engineering (Author)
  • T. Jüngst - , University of Würzburg (Author)
  • J. Malda - , Utrecht University (Author)
  • V. A. Mironov - , 3D Bioprinting Solutions, Sechenov First Moscow State Medical University (Author)
  • K. Nakayama - , Saga University (Author)
  • A. Ovsianikov - , Additive Manufacturing Technologies (AMT) Group, Austrian Cluster for Tissue Regeneration (Author)
  • W. Sun - , Tsinghua University, Drexel University College of Engineering (Author)
  • S. Takeuchi - , The University of Tokyo (Author)
  • J. J. Yoo - , Wake Forest University (Author)
  • T. B.F. Woodfield - , University of Otago (Author)

Abstract

Biofabrication aims to fabricate biologically functional products through bioprinting or bioassembly (Groll et al 2016 Biofabrication 8 013001). In biofabrication processes, cells are positioned at defined coordinates in three-dimensional space using automated and computer controlled techniques (Moroni et al 2018 Trends Biotechnol. 36 384-402), usually with the aid of biomaterials that are either (i) directly processed with the cells as suspensions/dispersions, (ii) deposited simultaneously in a separate printing process, or (iii) used as a transient support material. Materials that are suited for biofabrication are often referred to as bioinks and have become an important area of research within the field. In view of this special issue on bioinks, we aim herein to briefly summarize the historic evolution of this term within the field of biofabrication. Furthermore, we propose a simple but general definition of bioinks, and clarify its distinction from biomaterial inks.

Details

Original languageEnglish
Article number013001
JournalBiofabrication
Volume11
Issue number1
Publication statusPublished - Jan 2019
Peer-reviewedYes

External IDs

PubMed 30468151
ORCID /0000-0001-9075-5121/work/160047983

Keywords

Keywords

  • Bioink, Biomaterial ink, Definition