α3β1 is INTEGRAL to septic neutrophils

Research output: Contribution to journalComment/DebateContributedpeer-review

Contributors

Abstract

In this issue of Blood, Lerman et al1 identify the α3β1 integrin as a novel marker for hyperactivated neutrophils in septic patients and septic mice and provide functional evidence that this integrin contributes significantly to neutrophil infiltration and hyperresponsiveness in sepsis. Thus, α3β1 integrin could represent a novel and specific therapeutic target for sepsis.

Details

Original languageEnglish
Pages (from-to)3507-3508
Number of pages2
JournalBlood
Volume124
Issue number24
Publication statusPublished - 4 Dec 2014
Peer-reviewedYes

External IDs

Scopus 84916627621
PubMed 25477480
researchoutputwizard legacy.publication#60870

Keywords