1598. Clinical implications of azole-resistant vs. azole-susceptible invasive aspergillosis in hematological malignancy (CLARITY) – a multicenter study

Research output: Contribution to journal › Meeting abstract › Contributed › peer-review

Contributors

  • Danila Seidel - , University Hospital Cologne (Author)
  • Oliver Cornely - , University of Cologne, University Hospital Cologne (Author)
  • Marouan Zarrouk - , University Hospital Cologne (Author)
  • Philipp Koehler - , University Hospital Cologne (Author)
  • Jacques F Meis - , Canisius Wilhelmina Hospital (Author)
  • Jon Salmanton-García - , University of Cologne, University Hospital Cologne (Author)
  • Jörg Janne Vehreschild - , University Hospital Cologne (Author)
  • Martin Christner - , University Hospital Hamburg Eppendorf (Author)
  • Stefanie K Gräfe - , University Hospital Cologne, University of Hamburg, University Hospital Hamburg Eppendorf (Author)
  • Iker Falces-Romero - , La Paz University Hospital (Author)
  • Katrien Lagrou - , KU Leuven (Author)
  • Johan Maertens - , KU Leuven (Author)
  • Agustín Reséndiz- Sharpe - , KU Leuven (Author)
  • Zdenek Racil - , Institute of Hematology and Blood Transfusion (Author)
  • Barbora Weinbergerová - , University Hospital Brno (Author)
  • Maricela Valerio - , Hospital General Universitario Gregorio Marañon (Author)
  • Patricia Muñoz - , Hospital General Universitario Gregorio Marañon (Author)
  • Ola Blennow - , Karolinska University Hospital (Author)
  • Blandine Rammaert - , CHU de Poitiers (Author)
  • Alen Ostojic - , University Hospital Center Zagreb (Author)
  • Yohann Le Govic - , University Hospital Angers (Author)
  • Cornelia Lass-Flörl - , Innsbruck Medical University (Author)
  • Susann Rössler - , Institute of Medical Microbiology and Virology (Author)
  • Karin van Dijk - , Amsterdam University Medical Centers (UMC) (Author)
  • Nick de Jong - , Amsterdam University Medical Centers (UMC) (Author)
  • Jörg Steinmann - , Paracelsus Medical University Nuremberg (Author)
  • Guillaume Desoubeaux - , Université de Tours (Author)
  • Nael Alakel - , Department of Internal Medicine I, University Hospital Carl Gustav Carus Dresden (Author)
  • Nikolay Klimko - , North-Western State Medical University named after I.I. Mechnikov (Author)
  • Enrico Schalk - , Otto von Guericke University Magdeburg (Author)
  • Marie-Pierre Brenier-Pinchart - , CHU de Grenoble (Author)
  • Carolina Garcia-Vidal - , Hospital Clinic of Barcelona (Author)
  • Anne Bergeron - , Universite Paris 7 (Author)
  • Sung-Yeon Cho - , Catholic University of Korea (Author)
  • Willem J G Melchers - , Radboud University Medical Center (Author)
  • Maria J G T Vehreschild - , University of Cologne, University Hospital Cologne (Author)
  • Paul E Verweij - , Radboud University Medical Center (Author)

Abstract

Advances in the survival of patients with invasive aspergillosis (IA) are jeopardized by the emergence of azole resistance in Aspergillus fumigatus, which has been associated with high probability of azole treatment failure. The clinical implications of azole-resistant IA compared to azole-susceptible IA remain unclear. Thus, we seek to describe the epidemiology and to determine the efficacy of antifungal therapy in patients with documented azole-resistant IA compared to azole-susceptible IA in patients with hematological malignancy.

Details

Original languageEnglish
Pages (from-to)S795-S796
JournalOpen forum infectious diseases
Volume7
Issue numberSuppl 1
Publication statusPublished - 31 Dec 2020
Peer-reviewedYes

External IDs

crossref 10.1093/ofid/ofaa439.1778

Keywords