Thalassiosira pseudonana(Cyclotella nana) (Hustedt) Hasle et Heimdal (Bacillariophyceae): A genetically tractable model organism for studying diatom biology, including biological silica formation

Publikation: Beitrag in FachzeitschriftForschungsartikelEingeladenBegutachtung


In 2004, Thalassiosira pseudonana was the first eukaryotic marine alga to have its genome sequenced. Since then, this species has quickly emerged as a valuable model species for investigating the molecular underpinnings of essentially all aspects of diatom life, particularly bio-morphogenesis of the cell wall. An important prerequisite for the model status of T. pseudonana is the ongoing development of increasingly precise tools to study the function of gene networks and their encoded proteins in vivo. Here, we briefly review the current toolbox for genetic manipulation, highlight specific examples of its application in studying diatom metabolism, and provide a peek into the role of diatoms in the emerging field of silica biotechnology.


Seiten (von - bis)809-817
FachzeitschriftJournal of Phycology
Frühes Online-DatumJuli 2023
PublikationsstatusVeröffentlicht - Okt. 2023

Externe IDs

PubMed 37424141
Scopus 85164589452
Mendeley d0487a1c-eb4e-3698-bb4a-5eabd0e93ca0
ORCID /0000-0002-4533-8860/work/142241046


DFG-Fachsystematik nach Fachkollegium

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Ziele für nachhaltige Entwicklung


  • Algae, Diatom, Genetic engineering, Model, Molecular, algae, diatom, genetic engineering, model, molecular, Biology, Diatoms/genetics, Silicon Dioxide/metabolism, Genome