In order to exploit the full lightweight potential of hybrid adhesive joints, appl ication orientated dimensioning and assessment methods need be developed further. This refers in particular to fatigue loading of hybrid joints under multi-axial stress states which generate significant out-of-plane stresses in the fibre reinforced component. The work presented here focuses on the CFRP material in so called semi-structural hybrid adhesive joints, in which a thick layer of polyurethane adh esive is used to bond the material to the joining partner aluminium. A testing strategy is proposed in cluding in-plane and out-of-plane characterisation of the CFRP under static and cyclic loading as wel l as specific methods for service strength prediction. Finally, an outlook is given on the superordinate mmeta modelling strategy which incorporates a sophisticated submodel of the entire hybrid joint to p rovide precalculated results for efficient service strength analysis on full structure scale.