Seizure forecasting with ultra long-term EEG signals
Publikation: Beitrag in Fachzeitschrift › Forschungsartikel › Beigetragen › Begutachtung
Beitragende
Abstract
Objective: The apparent randomness of seizure occurrence affects greatly the quality of life of persons with epilepsy. Since seizures are often phase-locked to multidien cycles of interictal epileptiform activity, a recent forecasting scheme, exploiting RNS data, is capable of forecasting seizures days in advance. Methods: We tested the use of a bandpass filter to capture the universal mid-term dynamics enabling both patient-specific and cross-patient forecasting. In a retrospective study, we explored the feasibility of the scheme on three long-term recordings obtained by the NeuroPace RNS System, the NeuroVista intracranial, and the UNEEG subcutaneous devices, respectively. Results: Better-than-chance forecasting was observed in 15 (83 %) of 18 patients, and in 16 (89 %) patients for daily and hourly forecast, respectively. Meaningful forecast up to 30 days could be achieved in 4 (22 %) patients for hourly forecast frequency. The cross-patient performance decreased only marginally and was patient-wise strongly correlated with the patient-specific one. Comparable performance was obtained for NeuroVista and UNEEG data sets. Significance: The feasibility of cross-patient forecasting supports the universal importance of mid-term dynamics for seizure forecasting, demonstrates promising inter-subject-applicability of the scheme on ultra long-term EEG recordings, and highlights its huge potential for clinical use.
Details
Originalsprache | Englisch |
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Seiten (von - bis) | 211-220 |
Seitenumfang | 10 |
Fachzeitschrift | Clinical Neurophysiology |
Jahrgang | 167 |
Publikationsstatus | Veröffentlicht - Nov. 2024 |
Peer-Review-Status | Ja |
Externe IDs
ORCID | /0000-0001-7436-0103/work/172566318 |
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ORCID | /0000-0001-9875-3534/work/172568323 |
Schlagworte
ASJC Scopus Sachgebiete
Schlagwörter
- Cross-patient forecasting, Cycles in epilepsy, Seizure forecasting