The Score-P measurement infrastructure is a highly scalable and easy-to-use tool suite for profiling, event tracing, and online analysis of HPC applications. Score-P offers the user a maximum of convenience by supporting a number of analysis tools. Currently, it works with CubeGUI, Scalasca trace tools, Vampir, Tau, and Extra-P and is open for other tools. Score-P comes together with the new Open Trace Format Version 2, the Cube4 profiling format and the Opari2 instrumenter. Score-P is available under the 3-clause BSD Open Source license.