Non-Gaussian curvature distribution of actin-propelled biomimetic colloid trajectories
Publikation: Beitrag in Fachzeitschrift › Forschungsartikel › Beigetragen › Begutachtung
Beitragende
Abstract
We analyze the motion of colloids propelled by a comet-like tail of polymerizing actin filaments. The curvature of the particle trajectories deviates strongly from a Gaussian distribution, implying that the underlying microscopic processes are fluctuating in a non-independent manner. Trajectories for beads of different size all showed the same non-Gaussian behavior, while the mean curvature decreased weakly with size. A stochastic simulation that includes nucleation, force-dependent dissociation, growth, and capping of filaments, shows that the non-Gaussian curvature distribution can be explained by a positive feedback mechanism in which attached chains under higher tension are more likely to snap.
Details
Originalsprache | Englisch |
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Seiten (von - bis) | 1361-1366 |
Seitenumfang | 6 |
Fachzeitschrift | European biophysics journal : with biophysics letters |
Jahrgang | 37 |
Ausgabenummer | 8 |
Publikationsstatus | Veröffentlicht - Okt. 2008 |
Peer-Review-Status | Ja |
Extern publiziert | Ja |
Externe IDs
PubMed | 18491086 |
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Schlagworte
ASJC Scopus Sachgebiete
Schlagwörter
- Actin, Propulsion, Stochastic simulation, Trajectory analysis