Morphologic analysis of the human tympanic membrane by polarization-sensitive OCT and polarized light microscopy

Publikation: Beitrag in Buch/Konferenzbericht/Sammelband/GutachtenBeitrag in KonferenzbandBeigetragenBegutachtung

Abstract

The collagen layer of the human tympanic membrane (TM), which is essential for sound conduction and hearing, can be assessed in vivo by using endoscopic polarization-sensitive optical coherence tomography (PS-OCT), as we have shown recently. Since the resolution of the utilized system was limited, an ex vivo validation of the structural information is presented here. By comparing higher resolution PS-OCT images of a temporal bone specimen and polarized light microscopy (PLM) of histological slices from that TM with picrosirius red staining, the microstructure is investigated.

Details

OriginalspracheEnglisch
TitelOptical Coherence Imaging Techniques and Imaging in Scattering Media V
Redakteure/-innenBenjamin J. Vakoc, Maciej Wojtkowski, Yoshiaki Yasuno
Herausgeber (Verlag)SPIE - The international society for optics and photonics, Bellingham
ISBN (elektronisch)9781510664739
PublikationsstatusVeröffentlicht - 2023
Peer-Review-StatusJa

Publikationsreihe

ReiheProceedings of SPIE - The International Society for Optical Engineering
Band12632
ISSN0277-786X

Konferenz

TitelOptical Coherence Imaging Techniques and Imaging in Scattering Media V
Veranstaltungsnummer5
Dauer25 - 29 Juni 2023
BekanntheitsgradInternationale Veranstaltung
StadtMünchen
LandDeutschland

Externe IDs

ORCID /0000-0002-8047-2774/work/145223881
ORCID /0009-0002-1419-8698/work/145224173
ORCID /0000-0002-8160-3000/work/145224308
ORCID /0000-0003-0554-2178/work/145224487
ORCID /0009-0008-7642-8608/work/145224876

Schlagworte

Schlagwörter

  • birefringence, collagen, ear drum, optical coherence tomography, polarimetry