The paper presents the simulation methodology for a hybrid engine structure for future jet engine generations in the context of the whole engine model. In the complex system of a jet engine, the linkage of component simulation models to each other enables the analysis of the interactions and the improvement of the iterative development. The increasing requirements regarding the engine efficiency demand innovative design and manufacturing technologies, which lead to ever more complex models. Load path optimized variable-axial composite structures are to be considered on system model level to determine the structural behaviour under representative engine loads. To implement this approach, a suitable simulation strategy is developed. The following multiscale approach describes the modelling on component and sub-system level up to the integration into the whole engine model. The extraction of interface loads and retransfer on component level for further structural analysis is shown and validated. The elaborated virtual development method allows an effective but iterative design of all components of the hybrid intermediate case, taking the system conditions into account.