Fold-Hopf bursting in a model for calcium signal transduction

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

  • L Brusch - , Max-Planck-Institute for the Physics of Complex Systems (Autor:in)
  • W Lorenz - (Autor:in)
  • M Or-Guil - (Autor:in)
  • M Bar - (Autor:in)
  • U Kummer - (Autor:in)

Abstract

We study a recent model for calcium Signal transduction. This model displays spiking, bursting and chaotic oscillations in accordance with experimental results. We calculate bifurcation diagrams and study the bursting behaviour in detail. This behaviour is classified according to the dynamics of separated slow and fast subsystems. It is shown to be of the Fold-Hopf type, a type which was previously only described in the context of neuronal systems, but not in the context of signal transduction in the cell.

Details

OriginalspracheEnglisch
Seiten (von - bis)487-497
Seitenumfang11
FachzeitschriftZeitschrift fur Physikalische Chemie
Jahrgang216
Ausgabenummer4
PublikationsstatusVeröffentlicht - 2002
Peer-Review-StatusJa
Extern publiziertJa

Externe IDs

Scopus 85026128927
ORCID /0000-0003-0137-5106/work/142244238

Schlagworte

Schlagwörter

  • bursting oscillations, signal transduction, calcium, GENE-EXPRESSION, OSCILLATIONS, BIFURCATIONS, MECHANISMS, FREQUENCY, SYSTEM, CHAOS