Erratum: Corrigendum to “Short-range cytokine gradients to mimic paracrine cell interactions in vitro” (Journal of Controlled Release (2016) 224 (59–68) (S0168365915303047) (10.1016/j.jconrel.2015.12.053))

Publikation: Spezielle Publikationen/BeiträgeKorrekturen (Errata und Widerrufe)Begutachtung

Beitragende

  • Michael Ansorge - , Universität Leipzig (Autor:in)
  • Nadine Rastig - , Universität Leipzig (Autor:in)
  • Ralph Steinborn - , Universität Leipzig (Autor:in)
  • Tina König - , Universität Leipzig (Autor:in)
  • Lars Baumann - , Universität Leipzig (Autor:in)
  • Stephanie Möller - , Innovent e.V. (Autor:in)
  • Matthias Schnabelrauch - , Innovent e.V. (Autor:in)
  • Michael Cross - , Universität Leipzig (Autor:in)
  • Carsten Werner - , Center for Regenerative Therapies Dresden (CRTD), Professur für Biofunktionale Polymermaterialien (gB/IPF), Max Bergmann Zentrum für Biomaterialien Dresden (MBZ), Leibniz-Institut für Polymerforschung Dresden (Autor:in)
  • Annette G. Beck-Sickinger - , Universität Leipzig (Autor:in)
  • Tilo Pompe - , Universität Leipzig, Leibniz-Institut für Polymerforschung Dresden (Autor:in)

Abstract

The authors regret that: 1. The published Eq. (2) is correct, but describes the release into the surrounding media and not the decreasing amount of released protein in the μ-beads. However, the latter was measured and presented in the paper. For correctness the leading term (1-) has to be eliminated. Then the correct Eq. (2) already used for fitting the release data reads as follows: cc0=6π2∑n=1∞1n2exp−DBeadn2π2ta2 2. There is a scaling error for the determined diffusion coefficients inside the μ-beads DBead, which occurred in the fitting process. μm2/h was wrongly used instead of μm2/s. This affects Table 2 and two statements in the main text including comparisons to diffusion coefficients in solution. The corrected DBead is smaller by a factor of 3600. This fact more strongly underlines the slow diffusion inside the μ-bead and the validity of our assumptions. Hence, numbers for DBead in Table 2 have to be corrected (see below). The main text has to be changed.The sentences (last two sentences on page 63): ‘A fit of the model to the data reveals a diffusion coefficient inside the μ-beads DBead of roughly 0.2 μm2/s (Table 2). This diffusion coefficient is three orders of magnitude smaller than D for free diffusion of lysozyme, which is about 100 μm2/s [57].’ should read as: ‘A fit of the model to the data reveals a diffusion coefficient inside the μ-beads DBead of roughly 4 × 10–5 μm2/s (Table 2). This diffusion coefficient is six orders of magnitude smaller than D for free diffusion of lysozyme, which is about 100 μm2/s [57].’ The sentence (page 65, right column): ‘From the fits of Eq. (2) to the SDF-1 release data, SDF-1 mobility inside the μ-beads (DBead) was around 0.3 μm2/s and therefore in the same range as for lysozyme.’ should read as: ‘From the fits of Eq. (2) to the SDF-1 release data, SDF-1 mobility inside the μ-beads (DBead) was around 8 × 10–5 μm2/s and therefore in the same range as for lysozyme.’ The authors would like to apologise for any inconvenience caused.

Details

OriginalspracheEnglisch
Seiten243
Seitenumfang1
Band241
FachzeitschriftJournal of controlled release
PublikationsstatusVeröffentlicht - 10 Nov. 2016
Peer-Review-StatusJa
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Schlagworte

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