This paper examines the role of 5G communication in the Mobilities for EU project, a collaborative initiative involving 29 partners and 11 pilots aimed at revolutionizing urban mobility through electrification, automation, and connectivity. Focusing on Dresden as a Lead City, we explore the integration of 27 innovative solutions, including autonomous freight transport, eBuses, and charging robots, using a 5G communication network as the central framework. We analyze how 5G enables seamless connectivity and real-time data processing across diverse technologies, fostering interdependencies and synergies. This approach not only provides a cohesive understanding of the project’s scope but also demonstrates 5G’s critical role in smart city infrastructure. We evaluate the anticipated impact on sustainability metrics such as air quality, noise levels, CO2 emissions, and traffic congestion. The paper concludes by discussing challenges and strategies in leveraging 5G for comprehensive urban mobility solutions and its potential impact on future smart city developments.