Dissociating neural learning signals in human sign- and goal-trackers
Publikation: Beitrag in Fachzeitschrift › Forschungsartikel › Beigetragen › Begutachtung
Beitragende
Abstract
Individuals differ in how they learn from experience. In Pavlovian conditioning models, where cues predict reinforcer delivery at a different goal location, some animals—called sign-trackers—come to approach the cue, whereas others, called goal-trackers, approach the goal. In sign-trackers, model-free phasic dopaminergic reward-prediction errors underlie learning, which renders stimuli ‘wanted’. Goal-trackers do not rely on dopamine for learning and are thought to use model-based learning. We demonstrate this double dissociation in 129 male humans using eye-tracking, pupillometry and functional magnetic resonance imaging informed by computational models of sign- and goal-tracking. We show that sign-trackers exhibit a neural reward prediction error signal that is not detectable in goal-trackers. Model-free value only guides gaze and pupil dilation in sign-trackers. Goal-trackers instead exhibit a stronger model-based neural state prediction error signal. This model-based construct determines gaze and pupil dilation more in goal-trackers.
Details
Originalsprache | Englisch |
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Seiten (von - bis) | 201-214 |
Seitenumfang | 14 |
Fachzeitschrift | Nature human behaviour |
Jahrgang | 4 |
Ausgabenummer | 2 |
Publikationsstatus | Veröffentlicht - 1 Feb. 2020 |
Peer-Review-Status | Ja |
Externe IDs
PubMed | 31712764 |
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ORCID | /0000-0001-5398-5569/work/163294559 |